ScholarWorks@성균관대학교

초록

Electrochemiluminescence (ECL) has emerged as a pivotal technology in the field of biosensing because of its advantages with low background noise and high sensitivity. Its performance depends mainly on the efficiency of luminophores. Crystalline porous materials, such as metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen-bonded organic frameworks (HOFs), can offer an ideal platform for developing high-performance ECL materials, owing to their characteristics of tunable structure and feasible functionalization. However, the inherent properties of these materials pose constraints on their ECL performance. This review summarizes systematically recent advances within the last six years in boosting ECL of organic framework through the design of functional modules. It also demonstrates the applications of functionalized materials in biosensing, such as the detection of disease biomarkers and the analysis of environmental and food pollutants, as well as highlight the great potential of the “structure-function” integrated design. This review aims at providing theoretical guidance for designing high-performance ECL materials and to promoting the further development of crystalline porous framework materials in chemical analysis and biomolecule detection.

키워드