Different risk factors between bony and ligamentous proximal junctional failure in patients undergoing thoracolumbar fusion to pelvis for adult spinal deformity
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Study design: Retrospective study Objective: To analyze the risk factors for bony proximal junctional failure (B-PJF) and ligamentous PJF (L-PJF) separately after adult spinal deformity (ASD) surgery Summary of Background Data: Despite numerous studies about the risk factors of PJF, it remains unclear whether same risk factors can be applied to both B-PJF and L-PJF. Methods: Patients who underwent corrective surgery from low thoracic level (T9-T12) to pelvis with minimum follow-up duration of two years were included in this study. Patients with PJF were divided into two groups according to the involvement of bony structure: B-PJF and L-PJF. The control group was created using patients who did not develop PJF for ≥ 2 years postoperatively (no-PJF group). Risk factors were analyzed by comparing various clinical and radiographic parameters between no PJF versus B-PJF group and between no PJF versus L-PJF groups. Results: The final study cohort comprised 240 patients. The mean age was 68.7 years, and there were 205 women (85.4%). On average, 8.1 levels were fused. PJF developed in 103 patients, with 70 (68.0%) in the B-PJF group and 33 (32.0%) in the L-PJF group. Stepwise logistic regression analyses revealed that older age (odds ratio [OR] = 1.088), higher body mass index (BMI) (OR = 1.161), osteoporosis (OR = 3.293), greater postoperative lumbar distribution index (OR = 1.032), and overcorrection relative to the age-adjusted pelvic incidence - lumbar lordosis (OR = 3.964) were significant risk factors for B-PJF. Meanwhile, no use of transverse process (TP) hook was the single risk factor for L-PJF (OR = 4.724). Conclusions: Understanding the difference in risk factors between B-PJF and L-PJF will facilitate the optimization of surgical outcome for patients with ASD. Appropriate correction of sagittal malalignment along with use of TP hook is advisable to mitigate both B-PJF and L-PJF development. © 2024 Wolters Kluwer Health, Inc. All rights reserved.

키워드

Adult spinal deformityBony proximal junctional failureLigamentous proximal junctional failureProximal junctional failureRisk factorTransverse process hookLONG INSTRUMENTED FUSIONADJUSTED ALIGNMENT GOALSSAGITTAL ALIGNMENTSURGICAL-TREATMENTELDERLY-PATIENTSKYPHOSISSURGERYVERTEBRAVALIDATIONTETHERS
제목
Different risk factors between bony and ligamentous proximal junctional failure in patients undergoing thoracolumbar fusion to pelvis for adult spinal deformity
저자
Park, Se-JunPark, Jin-SungKang, Dong-HoKang, MinwookJung, KyunghunLee, Chong-Suh
DOI
10.1097/BRS.0000000000005151
발행일
2025-08
유형
Article
저널명
Spine
50
15
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1065 ~ 1073