Retraction note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy (Nature, (2023), 616, 7957, (563-573), 10.1038/s41586-023-05771-9)
  • Ng, Kevin W.
  • Boumelha, Jesse
  • Enfield, Katey S. S.
  • Almagro, Jorge
  • Cha, Hongui
  • ... Lee, Se-Hoon
  • 외 325명
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Retraction to: Naturehttps://doi.org/10.1038/s41586-023-05771-9 The authors have retracted this article. An investigation by The Francis Crick institute found concerns regarding some of the data presented in the figures, specifically: 1. The A549 cell binding data in Fig. 5c are manipulated and could not be reproduced. 2. The antibody-dependent cellular cytotoxicity (ADCC) experiments shown in Fig. 5d and 5e may contain manipulated data. 3. The integrity of the source data for the B cell and antibody quantitation in Fig. 3c and Extended Data Fig. 5c could not be verified. The Francis Crick Institute’s investigation found that co-first author Kevin Ng was responsible for these analyses. The investigation recommended that the paper be retracted. A statement concerning the investigation is available on The Francis Crick Institute’s website (https://www.crick.ac.uk/about-us/our-approach-to-science/research-integrity/2025-research-integrity-news). The authors apologize to the scientific community for any confusion and misunderstanding that may have arisen. They are committed to publishing a revised and properly validated research report in the near future. There is no indication that the investigation’s findings impact the integrity of the TRACERx and CAPTURE clinical and genetic data associated with this work.

제목
Retraction note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy (Nature, (2023), 616, 7957, (563-573), 10.1038/s41586-023-05771-9)
저자
Ng, Kevin W.Boumelha, JesseEnfield, Katey S. S.Almagro, JorgeCha, HonguiPich, OriolKarasaki, TakahiroMoore, David A.Salgado, RobertoSivakumar, MonicaYoung, GeorgeMolina-Arcas, Miriamde Carné Trécesson, SophieAnastasiou, PanayiotisFendler, AnnikaAu, LewisShepherd, Scott T. C.Martínez-Ruiz, CarlosPuttick, ClareBlack, James R. M.Watkins, Thomas B. K.Kim, HyeminShim, SeoheeFaulkner, NikhilAttig, JanVeeriah, SelvarajuMagno, NeilWard, SophiaFrankell, Alexander M.Al Bakir, MaiseLim, Emilia L.Hill, Mark S.Wilson, Gareth A.Cook, Daniel E.Birkbak, Nicolai J.Behrens, AxelYousaf, NadiaPopat, SanjayHackshaw, AllanYuan, YinyinDijkstra, KrijnSzallasi, ZoltanDiossy, MiklosSokac, MateoKisistok, JuditSchwarz, Roland F.Kaufmann, Tom L.Aerts, Hugo J. W. L.Joshi, VijayMoss, StuartShah, RajeshBishop, PaulJoseph, LeenaRammohan, KendadaiNovasio, JulietteDoran, HelenGranato, FeliceFontaine, EustaceSmith, ElaineMontero, AngelesDulloo, SeanMarrone, DomenicWilson, ClaireRathinam, SridharBoyles, RebeccaScotland, MollyChowdhry, Mohammed FiyazTufail, MohamadAng, KengFennell, Dean A.Sodha-Ramdeen, AzminaNakas, ApostolosBajaj, AmritaAustin, SilviaChee, SerenaIngram, PapawadeeScarlett, LydiaRichards, JenniferAlzetani, AimanKadiri, SalmaDjearaman, MadavaShackleford, HelenLangman, GeraldLacson, ChristerOsman, AyaPatel, Akshay J.Carter, MathewBrown, KateGomes, FabioLester, Jason F.Danson, SarahHewish, MadeleineRussell, PeterRobinson, LilyDick, CraigTotten, NicolaHodgkinson, Jack DaviesLeek, AngelaShackcloth, Michael J.Middleton, GaryBilancia, RoccoKostoulas, NikosAsif, MoThomas, MathewKirk, AlanSummers, YvonneKrebs, Matthew G.Blackhall, Fiona H.Lindsay, Colin R.Kerr, Keith M.Cave, JudithPrice, GillianCrosbie, PhilipOliveira, PedroPriest, LynseyTugwood, JonathanKilgour, ElaineRothwell, Dominic G.Dive, CarolineChaturvedi, AnshumanClipson, AlexandraKerr, AlastairBlyth, Kevin G.Le Quesne, JohnPrimrose, LindsayRiley, JoanShaw, Jacqui A.Matharu, GurdeepNaidu, BabuCruickshank, TraceyRichardson, ShirleyKhalil, MohammedCheyne, HeatherClark, TristanWong, Yien Ning SophiaBandula, SteveStephens, Robert C. M.Gorman, PatPanagiotopoulos, NikolaosHayward, MartinScarci, MarcoBhakhri, KunalChoudhary, JunaidHolding, James W.Monk, FleurMartinoni Hoogenboom, EmilieWu, YinSpanswick, VictoriaMourikis, Thanos P.Bola, Supreet KaurUng, Seng Kuong AnakinGamble, SamuelLópez, SaioaHynds, Robert E.Pawlik, PiotrChervova, OlgaLitovchenko, MariaVasquez, MarcosShah, MansiEnsell, LeahChen, KezhongSelvaraju, KayalvizhiHartley, John A.Reading, James L.Matos, IgnacioLowe, Helen L.Mastrokalos, GerasimosStavrou, GeorgiaGálvez-Cancino, FelipHoxha, ElenaKaragianni, DespoinaPearce, David R.Chain, BennyKaramani, AngelikiGilbert, KayleighPan, XiaoxiAbdulJabbar, KhalidZhang, HanyunGrapa, AncaRamsden, ZoeNaito, YutakaHill, WilliamLu, Wei-TingBarbè, VittorioDenner, TamaraBoeing, StefanVendramin, RobertoHobson, PhilipEscudero, MickaelGoldman, JackiGrönroos, EvaLevi, DinaWeeden, Clare E.Magness, AlastairStewart, AengusBoleti, EkateriniBegum, SofinaJordan, SimonBuderi, Silviu I.Booth, SarahShah, PratibhaDe Sousa, PauloFernandes, NadiaMalima, MphoAmbrose, LynRaubenheimer, HilgardtChavan, HemaBhayani, HarshilKaniu, DanielProli, ChiaraDevaraj, AnandRice, AlexandraBeck, StephanTanić, MiljanaJanes, Sam M.Ashford, PaulFraioli, FrancescoMacKenzie, MaireadChuter, DavidStone, Richard KevinNye, EmmaPatrini, DavideLawrence, DavidThakrar, Ricky M.Navani, NealTaylor, Magali N.Ahmed, AsiaNair, ArjunProcter, Alexander JamesCollins-Fekete, Charles-AntoineRoyle, GaryVeiga, CatarinaPeggs, Karl S.Van Loo, PeterDemeulemeester, JonasLarose Cadieux, ElizabethCastignani, CarlaHerrero, JavierLim, EricNicholson, Andrew G.Smith, SeanLeslie, RachelGower, NicoleChan, KittyDhanda, Harjot KaurPilotti, CamillaSharp, AbigailMarafioti, TeresaKhiroya, ReenaFalzon, MaryBorg, ElaineAhmad, TanyaBenafif, SarahWilson, JamesPapadatos-Pastos, DionysisLiu, Wing KinHessey, SonyaLee, Siow MingZaccaria, SimoneVanloo, SharonQuezada, Sergio A.Saghafinia, SadeghBentham, RobertPrymas, PaulinaKanu, NnennayaForster, Martin D.Werner Sunderland, MarianaThakkar, KrupaThol, KerstinLam, Jie MinGimeno-Valiente, FranciscoNaceur-Lombardelli, CristinaRichard, CorentinAbbosh, ChristopherToncheva, AntoniaBunkum, AbigailNicod, JeromeRosenthal, RachelAl-Sawaf, OthmanLucas, OliviaAngelova, MihaelaLeung, MichelleDietzen, MichelleGrigoriadis, KristianaRane, Jayant K.Zhai, HaoranAthanasopoulou, FoteiniColliver, EmmaBiswas, DhruvaLee, ClaudiaBailey, ChrisCampbell, Brittany B.Huebner, ArianaRowan, AndrewWilkinson, Robert J.Swerdlow, AnthonyWilkinson, Katalin A.Kumar, SacheenNicholson, EmmaPickering, LisaFurness, Andrew J. S.Young, KateReid, AlisonOkines, AliciaHarrington, KevinJhanji, ShamanTatham, Kate C.Banerjee, SusanaDroney, JoanneJones, Robin L.Welsh, LiamTurner, NicholasStarling, NaureenChau, IanCunningham, DavidMessiou, ChristinaSchmitt, Andreas M.Gerard, Camille L.Shum, BenjaminBoos, Laura AmandaByrne, FionaHiley, Crispin T.Litchfield, KevinMcGranahan, NicholasJamal-Hanjani, MariamLarkin, JamesLee, Se-HoonTurajlic, SamraSwanton, CharlesDownward, JulianKassiotis, George
DOI
10.1038/s41586-026-10104-7
발행일
2026
유형
Erratum
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