Advancements in Kidney-on-Chip: Antibiotic-Induced Kidney Injury and Future Directions
  • Kim, Min-Hyeok
  • Lee, Yugyeong
  • Seo, Gwang Myeong
  • Park, Sungsu
Citations

WEB OF SCIENCE

5
Citations

SCOPUS

4

초록

This review paper aims to critically assess the advancements, challenges, and future prospects of kidney-on-chip (KOC) technology in studying antibiotic-induced kidney injury. Despite significant progress, challenges such as limited throughput and the need for more accurate physiological replication persist. By analyzing current literature and technological developments, this review identifies key issues and outlines future directions for KOC research. Through an exploration of sensor integration, high-throughput screening capabilities, and automation, this review seeks to address these challenges and propel KOC toward more efficient and predictive drug-testing methodologies.

키워드

Kidney-on-chipAntibioticsKidney injuryOrgan-on-chipDesignRENAL PROXIMAL TUBULEA-CHIPELECTROCHEMICAL DETECTIONNEPHROTOXICITYCELLSAPOPTOSISMODELTECHNOLOGYSTRESS
제목
Advancements in Kidney-on-Chip: Antibiotic-Induced Kidney Injury and Future Directions
저자
Kim, Min-HyeokLee, YugyeongSeo, Gwang MyeongPark, Sungsu
DOI
10.1007/s13206-024-00160-4
발행일
2024-12
유형
Review; Early Access
저널명
BioChip Journal
18
4
페이지
535 ~ 545