ScholarWorks@성균관대학교

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김형식 프로필 사진

김형식

KIM, HYUNG SIK

약학대학

약학과

연구분야

- Pyruvate kinase M2 (PKM2)표적 기반 암세포 대사 조절 표적분자 발굴 및 기전연구: 암세포 대사과정에서 생성되는 유기산에 의한 저항성 획득 기전 및 전이에 미치는 영향를 통한 표적치료제 개발,
- 오믹스 기반 동물모델을 이용한 표적분자 독성 예측 바이오마커 발굴,
Histone deacetylase (HDAC) inhibitor의 항암활성 및 항암제 저항성 극복을 위한 기전연구

2013

2026

연도별 연구 활동 현황

자료유형

Article (268)

발행연도

2013 ~ 2026

2013 2026

언어

English (158)

전체 268건 중 1번부터 10번까지의 결과를 표시합니다.

2026

Article

An in vitro model of bleomycin-induced epithelial injury using stem cell-derived alveolar type 2 epithelial cells

Han, Yubin ;
Kim, Ha Ryong ;
Kim, Jun Woo ;
Shin, Tae Hwan ;
Kim, Hyung Sik ;
외 2명

2026-05-01
Toxicology Letters
Elsevier Ireland Ltd

Article

Epigenetic regulation of histone lysine demethylase 4B on cancer therapy in tamoxifen-sensitive and -resistant breast cancer cells.

Zheng, Tian ;
Kim, Ju Ri ;
Noh, Hyun Ji ;
Kim, Hyung Sik

2026-04-03
Cancer Research
AMER ASSOC CANCER RESEARCH

Article

A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells

Park, Jae Hyeon ;
Lee, Joo Chan ;
Sharma, Swati ;
Jiang, Chunxue ;
Lee, Haeun ;
... Park, Hyun-Ju ;
... Kim, Hyung Sik

2026-02-15
MedComm
John Wiley and Sons Inc

Article

Towards safer deep eutectic solvents: Insights from an in vivo study of reline toxicity under different preparation methods

Kang, Yua ;
Lee, Seong Min ;
Kang, Seulgi ;
Bae, Boyeon ;
Chen, Jingyan ;
... Shin, Beom Soo ;
... Kim, Hyung Sik ;
... Lee, Jeongmi ;
외 3명

2026-02-01
Journal of Hazardous Materials
Elsevier B.V.

Article

Effects of chloromethylisothiazolinone/methylisothiazolinone on cytotoxicity and mitochondrial dysfunction in bronchial epithelial cells

Lee, Eunah ;
Lee, Haeun ;
Park, Yong Joo ;
Chung, Kyu Hyuck ;
Kim, Hyung Sik

2026
Chemosphere
Elsevier Ltd

2025

Article

Surface charge-dependent toxicity of polystyrene nanoplastics in human lung epithelial BEAS-2B and HaCaT cells

Kyung, So Young ;
Kwack, Seung Jun ;
Lee, Byung Mu ;
Kim, Hyung Sik

2025-12
Journal of Toxicology and Environmental Health - Part A
TAYLOR & FRANCIS INC

Article

BKS-112, a Selective Histone Deacetylase 6 Inhibitor, Suppresses Triple-Negative Breast Cancer Cells via AKT/mTOR Pathway

Gali, Sreevarsha ;
Sharma, Swati ;
Noh, Hyunji ;
Kim, In Su ;
Kim, Hyung Sik

2025-10-28
ANTIOXIDANTS
MDPI

Article

HepatoToxicity Portal (HTP): an integrated database of drug-induced hepatotoxicity knowledgebase and graph neural network-based prediction model

Han, Jiyeon ;
Zhung, Wonho ;
Jang, Insoo ;
Lee, Joongwon ;
Kang, Min Ji ;
... Kim, Hyung Sik ;
외 7명

2025-04
Journal of Cheminformatics
BMC

Article

Photodynamic and sonodynamic therapy synergy: mechanistic insights and cellular responses against glioblastoma multiforme

Sharma, Swati ;
Gone, Geetanjali B. ;
Roychowdhury, Parikshit ;
Kim, Hyung Sik ;
Chung, Sang Jeon ;
외 2명

2025-04
Journal of Drug Targeting
TAYLOR & FRANCIS LTD

Article

An experimental and computational exploration on synthesis, structural elucidation, weaker interaction and anticancer activity analysis of novel progesterone oxadiazole derivative

Prakash ;
Rawat, Poonam ;
Sreevarsha, Gali ;
Chauhan, Manish Kumar ;
Ram, Anant ;
... Sik, Kim Hyung ;
외 4명

2025-03
Journal of Molecular Structure
Elsevier B.V.

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